Syphilis - An Old Though Thoroughly Modern Disease
Posted by: Elizabeth Campbell in HealthBy now you have known that syphilis is an STD that can generally be transmitted through sexual contact. It is a communicable disease, development of which is sure but may appear in an irregular manner. It is generally transmitted through direct contact of the infected genitals, and rarely by other means. It can damage any tissue or organ.
Primary syphilis is the stage where the Treponema Palladium spirochete enters the body which begins at the where the infectious sore directly touched; sometimes it does not show any remarkable symptom. Reviewing the medical history of the patient will reveal that the contact with an infected person happened 1-8 weeks before. The normal lesion is characterized by a chancre, a firm painless wound, the spot of the first exposure, most frequently, the penis, the labia or the uterine cervix.
The incubation takes on average 21 days, and it depends on more factors. The chancre begins with slight erosion, which changes rapidly into a superficial, painless ulceration. It is accompanied by hypertrophy of regional ganglions, which are isolated, mobile, and painless.
Secondary syphilis represents the dissemination period; it emerges at 7 - 10 weeks after the infecting contact and at 2 - 3 weeks since the occurrence of the primary syphilis sign, in the same time with microbes’ migration from ganglions where their number is big into circulation. A second incubation follows until the emergence of the first skin lesions, which occur after about 45 days since the first sign occurrence and 60 - 70 days since the infecting contact.
The patient will sometimes develop fever. Any tissue of the body can be affected and damaged. However, most of the lesion will appear in the teguments and mucous membranes. Tegument lesions will look like pustules despite its being akin to rashes caused by a viral disease.
Syphilis will occur recurrently if not diagnosed and treated correctly. This is when the infection will progress to the next stage, the secondary syphilis, 3 to 9 months after treatment. Relapses can be happening in the blood without any developing any outward symptoms. If manifestations appear, lesions will appear in the skin and mucous membranes. There will also be neurological and visceral symptoms, sore eyes; bones will be affected.
Latent syphilis represents a calm stage from clinical point of view, between secondary lesions resorption and tertiary symptoms emergence.
During this stage, the serologic reaction is positive, the LCR exam is negative; the radiological and clinical exam and the ECG highlight possible cardiovascular lesions.
The third stage of the infection or tertiary syphilis can emerge even after years of latency. At the late latency stage, lesions might appear perhaps as an allergic reaction of the tissue to Treponema Palladium, affecting tissues of the skin and the mucous membranes. Small lesions can develop and become nodules. The mucous membranes can also develop tubercles and lesions.
Congenital syphilis can be transmitted nowadays from mother to fetus, via fetus placenta flow, therefore during the baby’s intrauterine life. It cannot be transmitted from the father if the mother is healthy.
Precocious congenital syphilis is the type with which the child is born or it occurs during the first two years of life. It is characterized by blister like signs, sometimes ulcerous.
Late congenital syphilis sets off after two years from birth and the lesions that will appear denote that the disease is already in its third stage.

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